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IID50070
 UniprotP11927
ProteinCell division control protein KAR1
GeneKAR1
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
433
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 239-257 Hetero dimer : IID50065Complex
 Evidence NMR 1oqp B Reference
       Region 1oqp B 239-257 order
       Region 1oqp B 239-241 high_rmsd
       Region 1oqp B 255-257 high_rmsd
SeqProS possible 239-257 This region is described to be disordered in the free state. (PubMed=12842464) Hetero dimer : IID50065Complex
       Region 1oqp B 239-257 order
Seqphosphorylation
    233-233 Phosphothreonine
 
Prediction
NeProc
Disorder 1-202,224-253,269-331,374-392
Order 203-214,254-268,332-368,393-433
ProS 1-111,118-125,140-161,179-190,198-202,224-253,315-325,374-381,388-392
AlphaFold
Disorder 1-205,212-233,254-254,274-340,366-389,399-399,401-408,433-433
Order 206-211,234-253,255-273,341-365,390-398,400-400,409-432
SEG 208-219 ,322-331 ,417-431
Function
Function in SwissProt
KAR1 is required for function of both intranuclear and extranuclear microtubules. KAR1 helps localize CDC31 to the spindle pole body (SPB), CDC31 then initiates SPB duplication via interaction with a downstream effector.