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IID50101
 UniprotQ9JK83
ProteinPartitioning defective 6 homolog beta
GenePard6b
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
371
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 126-253 Hetero dimer : IID00308Complex
 Evidence X-RAY 1nf3 C Reference
       Region 1nf3 C 126-130 disorder
       Region 1nf3 C 131-253 order
 Evidence X-RAY 1nf3 D Reference
       Region 1nf3 D 126-130 disorder
       Region 1nf3 D 131-253 order
Seqphosphorylation
    11-11 Phosphoserine
    10-10 Phosphoserine
 
Prediction
NeProc
Disorder 1-12,108-142,252-371
Order 13-107,143-251
ProS 116-123,136-142,294-300,359-371
AlphaFold
Disorder 1-14,99-129,165-165,251-371
Order 15-98,130-164,166-250
Pfam Hmmer
PF00564 16-96 3e-21
PF00595 157-247 3.1e-11
SEG 250-275 ,287-301
Function
Function in SwissProt
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.