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IID50103
 UniprotQ9QX73
ProteinRho guanine nucleotide exchange factor 9
GeneArhgef9
OrganismRattus norvegicus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
493
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-493 Monomer :
 Evidence X-RAY 4mt6 A Reference
       Region 4mt6 A 1-17 disorder
       Region 4mt6 A 18-72 order
       Region 4mt6 A 73-105 disorder
       Region 4mt6 A 106-439 order
       Region 4mt6 A 440-456 disorder
 Evidence X-RAY 4mt7 A Reference
       Region 4mt7 A 10-104 disorder
       Region 4mt7 A 105-441 order
       Region 4mt7 A 442-493 disorder
Seq 71-463 Hetero dimer : IID00308Complex
 Evidence X-RAY 2dfk A Isoform 2 (UniProt identifier: Q9QX73-2) Reference
       Region 2dfk A 71-96 disorder
       Region 2dfk A 97-461 order
       Region 2dfk A 462-463 disorder
 Evidence X-RAY 2dfk C Isoform 2 (UniProt identifier: Q9QX73-2) Reference
       Region 2dfk C 71-104 disorder
       Region 2dfk C 105-457 order
       Region 2dfk C 458-463 disorder
 
Prediction
NeProc
Disorder 75-106,454-493
Order 1-74,107-453
ProS 75-89,454-458,479-485
AlphaFold
Disorder 1-16,28-31,73-105,460-493
Order 17-27,32-72,106-459
Pfam Hmmer
PF07653 19-72 9.1e-07
PF00621 114-293 1.6e-35
PF00169 326-432 2.4e-09
Function
Function in SwissProt
Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.