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IID50123
UniprotP51577
ProteinP2X purinoceptor 4
GeneP2rx4
OrganismRattus norvegicus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
388
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 111-167 Monomer :
 Evidence NMR 2rup A Reference
       Region 2rup A 111-167 order
Seq 375-384 Hetero dimer : IID50122Complex
 Evidence X-RAY 2bp5 P Reference
       Region 2bp5 P 375-384 order
SeqProS predicted 375-384 The unbound state of this region is deduced to be disordered based on the results of prediction tools (DICHOT, Mobi, d2p2 etc). Hetero dimer : IID50122Complex
       Region 2bp5 P 375-384 order
 
Prediction
NeProc
Disorder 1-3,380-388
Order 4-379
ProS 380-388
AlphaFold
Disorder 1-5,283-283,285-288,378-388
Order 6-282,284-284,289-377
Pfam Hmmer
PF00864 13-388 9.8e-288
SEG 359-374
Function
Function in SwissProt
Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.