Structure
atLeast majority ProS Experiment
:order disorder conflict PDB cluster ProS Pfam Domain SEG
126
order/disorder by at least rule
disorder by at least rule
order/disorder by majority rule
Seq 1-126 Hetero decamer : IID50067 Complex ,
IID50139 Complex ,
IID50145 Complex
Region 4ld9 H 1-34 disorder
Region 4ld9 H 35-122 order
Region 4ld9 H 123-126 disorder
Region 4ld9 D 1-37 disorder
Region 4ld9 D 38-123 order
Region 4ld9 D 124-126 disorder
Seq 1-126 Hetero 32mer : IID50139 Complex ,
IID50145 Complex
Region 5oy7 f 1-32 disorder
Region 5oy7 f 33-125 order
Region 5oy7 f 126-126 disorder
Region 5oy7 b 1-31 disorder
Region 5oy7 b 32-126 order
Region 5oy7 X 1-32 disorder
Region 5oy7 X 33-125 order
Region 5oy7 X 126-126 disorder
Region 5oy7 T 1-31 disorder
Region 5oy7 T 32-126 order
Region 5oy7 P 1-32 disorder
Region 5oy7 P 33-125 order
Region 5oy7 P 126-126 disorder
Region 5oy7 L 1-31 disorder
Region 5oy7 L 32-126 order
Region 5oy7 H 1-32 disorder
Region 5oy7 H 33-125 order
Region 5oy7 H 126-126 disorder
Region 5oy7 D 1-31 disorder
Region 5oy7 D 32-126 order
Seq 1-126 Hetero octamer : IID50145 Complex ,
Q6AZJ8
Region 3mgr H 2-27 disorder
Region 3mgr H 28-126 order
Region 3mgr D 2-27 disorder
Region 3mgr D 28-126 order
Region 3lz1 H 2-32 disorder
Region 3lz1 H 33-125 order
Region 3lz1 H 126-126 disorder
Region 3lz1 D 2-31 disorder
Region 3lz1 D 32-126 order
Region 3lz0 H 2-32 disorder
Region 3lz0 H 33-125 order
Region 3lz0 H 126-126 disorder
Region 3lz0 D 2-31 disorder
Region 3lz0 D 32-126 order
Region 3lel H 2-30 disorder
Region 3lel H 31-126 order
Region 3lel D 2-26 disorder
Region 3lel D 27-126 order
Region 3kxb H 5-30 disorder
Region 3kxb H 31-125 order
Region 3kxb H 126-126 disorder
Region 3kxb D 5-40 disorder
Region 3kxb D 41-126 order
Region 4kgc H 1-31 disorder
Region 4kgc H 32-126 order
Region 4kgc D 1-31 disorder
Region 4kgc D 32-126 order
Seq 1-126 Hetero hexadecamer : IID50139 Complex ,
IID50145 Complex
Region 5oxv R 1-32 disorder
Region 5oxv R 33-125 order
Region 5oxv R 126-126 disorder
Region 5oxv N 1-31 disorder
Region 5oxv N 32-126 order
Region 5oxv H 1-32 disorder
Region 5oxv H 33-125 order
Region 5oxv H 126-126 disorder
Region 5oxv D 1-31 disorder
Region 5oxv D 32-126 order
Seq 1-126 Hetero octamer : IID00019 Complex ,
P62806
Region 1f66 H 1-31 disorder
Region 1f66 H 32-126 order
Region 1f66 D 1-31 disorder
Region 1f66 D 32-126 order
Seq 2-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 4wu8 H 2-31 disorder
Region 4wu8 H 32-126 order
Region 4wu8 D 2-31 disorder
Region 4wu8 D 32-126 order
Region 3rei H 5-31 disorder
Region 3rei H 32-126 order
Region 3rei D 5-31 disorder
Region 3rei D 32-126 order
Region 3reh H 5-31 disorder
Region 3reh H 32-126 order
Region 3reh D 5-31 disorder
Region 3reh D 32-126 order
Region 1p3f H 2-31 disorder
Region 1p3f H 32-126 order
Region 1p3f D 2-35 disorder
Region 1p3f D 36-126 order
Region 1p3b H 2-34 disorder
Region 1p3b H 35-126 order
Region 1p3b D 2-32 disorder
Region 1p3b D 33-126 order
Region 5onw H 5-33 disorder
Region 5onw H 34-125 order
Region 5onw H 126-126 disorder
Region 5onw D 5-29 disorder
Region 5onw D 30-125 order
Region 5onw D 126-126 disorder
Region 3lja H 5-27 disorder
Region 3lja H 28-126 order
Region 3lja D 5-27 disorder
Region 3lja D 28-126 order
Region 5dnn H 2-31 disorder
Region 5dnn H 32-126 order
Region 5dnn D 2-31 disorder
Region 5dnn D 32-126 order
Region 5dnm H 2-31 disorder
Region 5dnm H 32-126 order
Region 5dnm D 2-31 disorder
Region 5dnm D 32-126 order
Seq 2-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 1m1a H 2-32 disorder
Region 1m1a H 33-125 order
Region 1m1a H 126-126 disorder
Region 1m1a D 2-32 disorder
Region 1m1a D 33-125 order
Region 1m1a D 126-126 disorder
Seq 2-126 Hetero octamer : IID50145 Complex ,
Q6AZJ8
Region 3mgs H 2-27 disorder
Region 3mgs H 28-126 order
Region 3mgs D 2-27 disorder
Region 3mgs D 28-126 order
Seq 2-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 4z66 H 34-126 order
Region 4z66 D 34-126 order
Region 4xzq H 34-126 order
Region 4xzq D 34-126 order
Region 5xf6 H 2-31 disorder
Region 5xf6 H 32-126 order
Region 5xf6 D 2-31 disorder
Region 5xf6 D 32-126 order
Region 4wu9 H 2-31 disorder
Region 4wu9 H 32-126 order
Region 4wu9 D 2-31 disorder
Region 4wu9 D 32-126 order
Region 3utb H 2-32 disorder
Region 3utb H 33-126 order
Region 3utb D 2-27 disorder
Region 3utb D 28-126 order
Region 3uta H 2-31 disorder
Region 3uta H 32-126 order
Region 3uta D 2-31 disorder
Region 3uta D 32-126 order
Region 3ut9 H 2-29 disorder
Region 3ut9 H 30-126 order
Region 3ut9 D 2-29 disorder
Region 3ut9 D 30-125 order
Region 3ut9 D 126-126 disorder
Region 1s32 H 5-28 disorder
Region 1s32 H 29-126 order
Region 1s32 D 5-25 disorder
Region 1s32 D 26-126 order
Region 3rel H 5-32 disorder
Region 3rel H 33-126 order
Region 3rel D 5-27 disorder
Region 3rel D 28-126 order
Region 3rek H 5-32 disorder
Region 3rek H 33-126 order
Region 3rek D 5-27 disorder
Region 3rek D 28-126 order
Region 3rej H 5-32 disorder
Region 3rej H 33-126 order
Region 3rej D 5-27 disorder
Region 3rej D 28-126 order
Region 1p3p H 2-30 disorder
Region 1p3p H 31-126 order
Region 1p3p D 2-33 disorder
Region 1p3p D 34-126 order
Region 1p3m H 2-35 disorder
Region 1p3m H 36-126 order
Region 1p3m D 2-34 disorder
Region 1p3m D 35-126 order
Region 1p3l H 2-31 disorder
Region 1p3l H 32-126 order
Region 1p3l D 2-34 disorder
Region 1p3l D 35-126 order
Region 1p34 H 2-31 disorder
Region 1p34 H 32-125 order
Region 1p34 H 126-126 disorder
Region 1p34 D 2-33 disorder
Region 1p34 D 34-125 order
Region 1p34 D 126-126 disorder
Region 5ong H 5-32 disorder
Region 5ong H 33-125 order
Region 5ong H 126-126 disorder
Region 5ong D 5-31 disorder
Region 5ong D 32-125 order
Region 5ong D 126-126 disorder
Region 3o62 H 5-31 disorder
Region 3o62 H 32-126 order
Region 3o62 D 5-31 disorder
Region 3o62 D 32-126 order
Region 2nzd H 2-31 disorder
Region 2nzd H 32-126 order
Region 2nzd D 2-31 disorder
Region 2nzd D 32-126 order
Region 3mnn H 2-31 disorder
Region 3mnn H 32-126 order
Region 3mnn D 2-31 disorder
Region 3mnn D 32-126 order
Region 1kx5 H 2-4 disorder
Region 1kx5 H 5-126 order
Region 1kx5 D 2-4 disorder
Region 1kx5 D 5-126 order
Region 1kx4 H 2-32 disorder
Region 1kx4 H 33-126 order
Region 1kx4 D 2-27 disorder
Region 1kx4 D 28-126 order
Region 1kx3 H 2-32 disorder
Region 1kx3 H 33-126 order
Region 1kx3 D 2-32 disorder
Region 1kx3 D 33-126 order
Region 3kwq H 34-126 order
Region 3kwq D 34-126 order
Region 3kuy H 2-31 disorder
Region 3kuy H 32-126 order
Region 3kuy D 2-31 disorder
Region 3kuy D 32-126 order
Region 5cp6 H 2-31 disorder
Region 5cp6 H 32-126 order
Region 5cp6 D 2-31 disorder
Region 5cp6 D 32-126 order
Region 3b6g H 2-27 disorder
Region 3b6g H 28-126 order
Region 3b6g D 2-25 disorder
Region 3b6g D 26-126 order
Seq 2-126 Hetero 32mer : IID50139 Complex ,
IID50145 Complex
Region 1zbb H 2-27 disorder
Region 1zbb H 28-126 order
Region 1zbb D 2-11 disorder
Region 1zbb D 12-17 order
Region 1zbb D 18-25 disorder
Region 1zbb D 26-126 order
Seq 2-126 Hetero tetramer : IID50139 Complex ,
IID50145 Complex
Region 5nl0 N 5-30 disorder
Region 5nl0 N 31-125 order
Region 5nl0 N 126-126 disorder
Region 4j8x H 2-31 disorder
Region 4j8x H 32-126 order
Region 4j8x D 2-31 disorder
Region 4j8x D 32-126 order
Region 4j8v H 2-31 disorder
Region 4j8v H 32-126 order
Region 4j8v D 2-31 disorder
Region 4j8v D 32-126 order
Seq 2-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 1m18 H 2-32 disorder
Region 1m18 H 33-126 order
Region 1m18 D 2-32 disorder
Region 1m18 D 33-126 order
Seq 2-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 2fj7 H 2-33 disorder
Region 2fj7 H 34-126 order
Region 2fj7 D 2-33 disorder
Region 2fj7 D 34-126 order
Region 3b6f H 2-27 disorder
Region 3b6f H 28-126 order
Region 3b6f D 2-25 disorder
Region 3b6f D 26-126 order
Seq 2-126 Hetero nonamer : IID50139 Complex ,
IID50145 Complex ,
Q9DUM3
Region 1zla H 2-33 disorder
Region 1zla H 34-126 order
Region 1zla D 2-33 disorder
Region 1zla D 34-126 order
Seq 2-126 Hetero tetramer : IID50139 Complex ,
IID50145 Complex
Region 4j8w D 2-31 disorder
Region 4j8w D 32-126 order
Region 4j8w H 2-31 disorder
Region 4j8w H 32-126 order
Region 4j8u D 2-31 disorder
Region 4j8u D 32-126 order
Region 4j8u H 2-31 disorder
Region 4j8u H 32-126 order
Seq 2-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 4ys3 H 34-126 order
Region 4ys3 D 34-126 order
Region 4xuj H 2-31 disorder
Region 4xuj H 32-126 order
Region 4xuj D 2-31 disorder
Region 4xuj D 32-126 order
Region 5omx H 5-30 disorder
Region 5omx H 31-125 order
Region 5omx H 126-126 disorder
Region 5omx D 5-32 disorder
Region 5omx D 33-126 order
Seq 2-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 1m19 H 2-32 disorder
Region 1m19 H 33-126 order
Region 1m19 D 2-32 disorder
Region 1m19 D 33-126 order
Seq 2-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 1p3o H 2-34 disorder
Region 1p3o H 35-126 order
Region 1p3o D 2-34 disorder
Region 1p3o D 35-126 order
Region 1p3k H 2-32 disorder
Region 1p3k H 33-126 order
Region 1p3k D 2-34 disorder
Region 1p3k D 35-126 order
Region 1p3i H 2-32 disorder
Region 1p3i H 33-126 order
Region 1p3i D 2-31 disorder
Region 1p3i D 32-126 order
Region 1p3g H 2-34 disorder
Region 1p3g H 35-126 order
Region 1p3g D 2-33 disorder
Region 1p3g D 34-126 order
Region 1p3a H 2-34 disorder
Region 1p3a H 35-126 order
Region 1p3a D 2-35 disorder
Region 1p3a D 36-126 order
Seq 2-126 Hetero octamer : IID50145 Complex ,
Q6AZJ8
Region 3mgq H 2-27 disorder
Region 3mgq H 28-126 order
Region 3mgq D 2-26 disorder
Region 3mgq D 27-126 order
Region 3mgp H 2-27 disorder
Region 3mgp H 28-126 order
Region 3mgp D 2-26 disorder
Region 3mgp D 27-126 order
Seq 2-126 Hetero octamer : IID50145 Complex ,
Q6AZJ8
Region 3lel R 2-30 disorder
Region 3lel R 31-126 order
Region 3lel N 2-30 disorder
Region 3lel N 31-126 order
Region 2f8n H 5-33 disorder
Region 2f8n H 34-126 order
Region 4zux R 5-32 disorder
Region 4zux R 33-125 order
Region 4zux R 126-126 disorder
Region 4zux N 5-31 disorder
Region 4zux N 32-126 order
Region 3mvd H 5-32 disorder
Region 3mvd H 33-125 order
Region 3mvd H 126-126 disorder
Region 3mvd D 5-32 disorder
Region 3mvd D 33-125 order
Region 3mvd D 126-126 disorder
Seq 5-126 Hetero dodecamer : IID50139 Complex ,
IID50145 Complex ,
P21827
Region 5hq2 H 5-31 disorder
Region 5hq2 H 32-126 order
Seq 5-126 Hetero nonamer : IID50139 Complex ,
IID50145 Complex
Region 5nl0 H 5-30 disorder
Region 5nl0 H 31-126 order
Region 5nl0 D 5-30 disorder
Region 5nl0 D 31-125 order
Region 5nl0 D 126-126 disorder
Region 4zux H 5-32 disorder
Region 4zux H 33-125 order
Region 4zux H 126-126 disorder
Region 4zux D 5-31 disorder
Region 4zux D 32-126 order
Seq 5-126 Hetero dodecamer : IID50139 Complex ,
IID50145 Complex ,
P61077 ,
Q99496
Region 4r8p H 5-31 disorder
Region 4r8p H 32-126 order
Region 4r8p D 5-31 disorder
Region 4r8p D 32-126 order
Seq 5-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 5f99 H 5-29 disorder
Region 5f99 H 30-126 order
Region 5f99 D 5-26 disorder
Region 5f99 D 27-126 order
Seq 5-126 Hetero nonamer : IID50139 Complex ,
IID50145 Complex ,
P03169
Region 5e5a H 5-31 disorder
Region 5e5a H 32-125 order
Region 5e5a H 126-126 disorder
Region 5e5a D 5-27 disorder
Region 5e5a D 28-125 order
Region 5e5a D 126-126 disorder
Seq 5-126 Hetero decamer : IID50067 Complex ,
IID50139 Complex ,
IID50145 Complex
Region 3tu4 H 5-32 disorder
Region 3tu4 H 33-125 order
Region 3tu4 H 126-126 disorder
Region 3tu4 D 5-32 disorder
Region 3tu4 D 33-125 order
Region 3tu4 D 126-126 disorder
Seq 28-126 Hetero tetramer : IID50139 Complex
Region 5g2e H 28-37 disorder
Region 5g2e H 38-126 order
Seq 28-126 Hetero octamer : IID50139 Complex ,
IID50145 Complex
Region 1aoi H 28-126 order
Region 1aoi D 28-126 order
Seq 28-126 Hetero tetramer : IID50139 Complex ,
P25293
Region 5g2e L 28-37 disorder
Region 5g2e L 38-126 order
Seq 28-126 Hetero tetramer : IID50139 Complex
Region 5g2e D 28-37 disorder
Region 5g2e D 38-126 order
Seq 28-126 Hetero tetramer : IID50139 Complex ,
P25293
Region 5g2e P 28-37 disorder
Region 5g2e P 38-126 order
Region 5g2e X 28-37 disorder
Region 5g2e X 38-126 order
Region 5g2e T 28-37 disorder
Region 5g2e T 38-126 order
Region 4kha A 34-125 order
Region 4kha A 126-126 disorder
Prediction
Disorder 1-1,3-3,14-14,23-34,126-126
Order 2-2,4-13,15-22,35-125
Function
Function in SwissProt
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.