Structure
atLeast majority ProS Experiment
:order disorder conflict PDB cluster ProS Pfam Domain SEG
103
order/disorder by at least rule
disorder by at least rule
order/disorder by majority rule
Seq 1-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 4wu8 F 2-16 disorder
Region 4wu8 F 17-103 order
Region 4wu8 B 2-21 disorder
Region 4wu8 B 22-103 order
Region 3rei F 2-16 disorder
Region 3rei F 17-103 order
Region 3rei B 2-21 disorder
Region 3rei B 22-103 order
Region 3reh F 2-16 disorder
Region 3reh F 17-103 order
Region 3reh B 2-21 disorder
Region 3reh B 22-103 order
Region 1p3f F 2-21 disorder
Region 1p3f F 22-103 order
Region 1p3f B 2-23 disorder
Region 1p3f B 24-103 order
Region 1p3b F 2-22 disorder
Region 1p3b F 23-103 order
Region 1p3b B 2-25 disorder
Region 1p3b B 26-103 order
Region 5onw F 1-17 disorder
Region 5onw F 18-103 order
Region 5onw B 1-25 disorder
Region 5onw B 26-103 order
Region 3lja F 2-16 disorder
Region 3lja F 17-103 order
Region 3lja B 2-24 disorder
Region 3lja B 25-103 order
Region 5dnn F 2-16 disorder
Region 5dnn F 17-103 order
Region 5dnn B 2-21 disorder
Region 5dnn B 22-103 order
Region 5dnm F 2-16 disorder
Region 5dnm F 17-103 order
Region 5dnm B 2-21 disorder
Region 5dnm B 22-103 order
Seq 1-103 Hetero decamer : IID50067 Complex ,
IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 4ld9 F 1-18 disorder
Region 4ld9 F 19-101 order
Region 4ld9 F 102-103 disorder
Region 4ld9 B 1-12 disorder
Region 4ld9 B 13-101 order
Region 4ld9 B 102-103 disorder
Region 2f8n F 1-19 disorder
Region 2f8n F 20-103 order
Region 2f8n B 1-24 disorder
Region 2f8n B 25-103 order
Seq 1-103 Hetero octadecamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 4zux P 1-25 disorder
Region 4zux P 26-103 order
Region 4zux L 1-20 disorder
Region 4zux L 21-103 order
Seq 1-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 4z66 F 22-103 order
Region 4z66 B 22-24 disorder
Region 4z66 B 25-103 order
Region 4xzq F 25-103 order
Region 4xzq B 25-103 order
Region 5xf6 F 2-16 disorder
Region 5xf6 F 17-103 order
Region 5xf6 B 2-21 disorder
Region 5xf6 B 22-103 order
Region 4wu9 F 2-16 disorder
Region 4wu9 F 17-103 order
Region 4wu9 B 2-21 disorder
Region 4wu9 B 22-103 order
Region 3utb F 2-25 disorder
Region 3utb F 26-103 order
Region 3utb B 2-20 disorder
Region 3utb B 21-103 order
Region 3uta F 2-16 disorder
Region 3uta F 17-103 order
Region 3uta B 2-21 disorder
Region 3uta B 22-103 order
Region 3ut9 F 2-16 disorder
Region 3ut9 F 17-103 order
Region 3ut9 B 2-24 disorder
Region 3ut9 B 25-103 order
Region 1s32 F 2-15 disorder
Region 1s32 F 16-103 order
Region 1s32 B 2-22 disorder
Region 1s32 B 23-103 order
Region 3rel F 2-25 disorder
Region 3rel F 26-103 order
Region 3rel B 2-20 disorder
Region 3rel B 21-103 order
Region 3rek F 2-25 disorder
Region 3rek F 26-103 order
Region 3rek B 2-20 disorder
Region 3rek B 21-103 order
Region 3rej F 2-25 disorder
Region 3rej F 26-103 order
Region 3rej B 2-20 disorder
Region 3rej B 21-103 order
Region 1p3p F 2-21 disorder
Region 1p3p F 22-103 order
Region 1p3p B 2-22 disorder
Region 1p3p B 23-103 order
Region 1p3m F 2-21 disorder
Region 1p3m F 22-103 order
Region 1p3m B 2-25 disorder
Region 1p3m B 26-103 order
Region 1p3l F 2-20 disorder
Region 1p3l F 21-103 order
Region 1p3l B 2-24 disorder
Region 1p3l B 25-103 order
Region 1p34 F 2-22 disorder
Region 1p34 F 23-103 order
Region 1p34 B 2-20 disorder
Region 1p34 B 21-103 order
Region 5ong F 1-19 disorder
Region 5ong F 20-103 order
Region 5ong B 1-25 disorder
Region 5ong B 26-103 order
Region 3o62 F 2-18 disorder
Region 3o62 F 19-102 order
Region 3o62 F 103-103 disorder
Region 3o62 B 2-23 disorder
Region 3o62 B 24-103 order
Region 2nzd F 2-16 disorder
Region 2nzd F 17-103 order
Region 2nzd B 2-21 disorder
Region 2nzd B 22-103 order
Region 3mnn F 2-16 disorder
Region 3mnn F 17-103 order
Region 3mnn B 2-21 disorder
Region 3mnn B 22-103 order
Region 1kx5 F 2-103 order
Region 1kx5 B 2-103 order
Region 1kx4 F 2-25 disorder
Region 1kx4 F 26-103 order
Region 1kx4 B 2-20 disorder
Region 1kx4 B 21-103 order
Region 1kx3 F 2-16 disorder
Region 1kx3 F 17-103 order
Region 1kx3 B 2-21 disorder
Region 1kx3 B 22-103 order
Region 3kwq F 21-103 order
Region 3kwq B 21-24 disorder
Region 3kwq B 25-103 order
Region 3kuy F 2-16 disorder
Region 3kuy F 17-103 order
Region 3kuy B 2-21 disorder
Region 3kuy B 22-103 order
Region 5cp6 F 2-16 disorder
Region 5cp6 F 17-103 order
Region 5cp6 B 2-21 disorder
Region 5cp6 B 22-103 order
Region 3b6g F 2-16 disorder
Region 3b6g F 17-103 order
Region 3b6g B 2-24 disorder
Region 3b6g B 25-103 order
Seq 1-103 Hetero octadecamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 4zux F 1-25 disorder
Region 4zux F 26-103 order
Region 4zux B 1-20 disorder
Region 4zux B 21-103 order
Seq 1-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 4ys3 F 25-103 order
Region 4ys3 B 25-103 order
Region 4xuj F 2-16 disorder
Region 4xuj F 17-103 order
Region 4xuj B 2-21 disorder
Region 4xuj B 22-103 order
Region 5omx F 1-17 disorder
Region 5omx F 18-103 order
Region 5omx B 1-24 disorder
Region 5omx B 25-103 order
Seq 1-103 Hetero nonamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 5e5a F 1-17 disorder
Region 5e5a F 18-103 order
Region 5e5a B 1-24 disorder
Region 5e5a B 25-103 order
Seq 1-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 5f99 F 1-11 disorder
Region 5f99 F 12-103 order
Region 5f99 B 1-20 disorder
Region 5f99 B 21-103 order
Seq 1-103 Hetero octamer : IID50135 Complex ,
IID50147 Complex ,
Q6AZJ8
Region 3mgr F 2-16 disorder
Region 3mgr F 17-103 order
Region 3mgr B 2-24 disorder
Region 3mgr B 25-103 order
Region 3lz1 F 2-25 disorder
Region 3lz1 F 26-103 order
Region 3lz1 B 2-20 disorder
Region 3lz1 B 21-103 order
Region 3lz0 F 2-25 disorder
Region 3lz0 F 26-103 order
Region 3lz0 B 2-20 disorder
Region 3lz0 B 21-103 order
Region 3lel F 2-17 disorder
Region 3lel F 18-103 order
Region 3lel B 2-24 disorder
Region 3lel B 25-103 order
Region 3kxb F 2-17 disorder
Region 3kxb F 18-103 order
Region 3kxb B 2-29 disorder
Region 3kxb B 30-103 order
Region 4kgc F 1-16 disorder
Region 4kgc F 17-103 order
Region 4kgc B 1-21 disorder
Region 4kgc B 22-103 order
Seq 2-103 Hetero nonamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 5nl0 F 2-20 disorder
Region 5nl0 F 21-103 order
Region 5nl0 B 2-20 disorder
Region 5nl0 B 21-103 order
Seq 2-103 Hetero 32mer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 5oy7 d 2-25 disorder
Region 5oy7 d 26-103 order
Region 5oy7 Z 2-20 disorder
Region 5oy7 Z 21-103 order
Region 5oy7 V 2-25 disorder
Region 5oy7 V 26-103 order
Region 5oy7 R 2-20 disorder
Region 5oy7 R 21-37 order
Region 5oy7 R 38-38 disorder
Region 5oy7 R 39-103 order
Region 5oy7 N 2-25 disorder
Region 5oy7 N 26-103 order
Region 5oy7 J 2-20 disorder
Region 5oy7 J 21-103 order
Region 5oy7 F 2-25 disorder
Region 5oy7 F 26-103 order
Region 5oy7 B 2-20 disorder
Region 5oy7 B 21-103 order
Seq 2-103 Hetero decamer : IID50135 Complex ,
IID50147 Complex ,
Q6AZJ8
Region 3mvd F 2-17 disorder
Region 3mvd F 18-103 order
Region 3mvd B 2-20 disorder
Region 3mvd B 21-102 order
Region 3mvd B 103-103 disorder
Seq 2-103 Hetero octamer : IID50135 Complex ,
IID50147 Complex ,
Q6AZJ8
Region 3mgs F 2-16 disorder
Region 3mgs F 17-103 order
Region 3mgs B 2-24 disorder
Region 3mgs B 25-103 order
Seq 2-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 2fj7 F 2-19 disorder
Region 2fj7 F 20-103 order
Region 2fj7 B 2-24 disorder
Region 2fj7 B 25-103 order
Region 3b6f F 2-16 disorder
Region 3b6f F 17-103 order
Region 3b6f B 2-24 disorder
Region 3b6f B 25-103 order
Seq 2-103 Hetero dodecamer : IID00101 Complex ,
IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 5hq2 B 2-24 disorder
Region 5hq2 B 25-102 order
Region 5hq2 B 103-103 disorder
Seq 2-103 Hetero 32mer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 1zbb F 7-11 disorder
Region 1zbb F 12-13 order
Region 1zbb F 14-16 disorder
Region 1zbb F 17-103 order
Region 1zbb B 2-21 disorder
Region 1zbb B 22-22 order
Region 1zbb B 23-24 disorder
Region 1zbb B 25-103 order
Seq 2-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
P02302
Region 1m1a F 2-10 disorder
Region 1m1a F 11-103 order
Region 1m1a B 2-23 disorder
Region 1m1a B 24-103 order
Seq 2-103 Hetero dodecamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 4r8p F 2-21 disorder
Region 4r8p F 22-103 order
Region 4r8p B 2-17 disorder
Region 4r8p B 18-103 order
Seq 2-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
P02302
Region 1m19 F 2-17 disorder
Region 1m19 F 18-103 order
Region 1m19 B 2-24 disorder
Region 1m19 B 25-103 order
Seq 2-103 Hetero pentamer : IID50147 Complex ,
Q68D10
Region 5bsa D 2-26 disorder
Region 5bsa D 27-94 order
Region 5bsa D 95-103 disorder
Region 5bsa C 2-27 disorder
Region 5bsa C 28-96 order
Region 5bsa C 97-103 disorder
Region 5bs7 D 2-26 disorder
Region 5bs7 D 27-94 order
Region 5bs7 D 95-103 disorder
Region 5bs7 C 2-27 disorder
Region 5bs7 C 28-96 order
Region 5bs7 C 97-103 disorder
Seq 2-103 Hetero nonamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 1zla F 2-19 disorder
Region 1zla F 20-103 order
Region 1zla B 2-24 disorder
Region 1zla B 25-103 order
Seq 2-103 Hetero tetramer : IID50135 Complex ,
IID50147 Complex
Region 5nl0 L 2-20 disorder
Region 5nl0 L 21-103 order
Region 4j8x F 2-16 disorder
Region 4j8x F 17-103 order
Region 4j8x B 2-21 disorder
Region 4j8x B 22-103 order
Region 4j8v F 2-16 disorder
Region 4j8v F 17-103 order
Region 4j8v B 2-21 disorder
Region 4j8v B 22-103 order
Seq 2-103 Hetero decamer : IID50067 Complex ,
IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 3tu4 F 2-13 disorder
Region 3tu4 F 14-103 order
Region 3tu4 B 2-13 disorder
Region 3tu4 B 14-102 order
Region 3tu4 B 103-103 disorder
Seq 2-103 Hetero hexadecamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 5oxv P 2-25 disorder
Region 5oxv P 26-103 order
Region 5oxv L 2-20 disorder
Region 5oxv L 21-103 order
Region 5oxv F 2-25 disorder
Region 5oxv F 26-103 order
Region 5oxv B 2-20 disorder
Region 5oxv B 21-103 order
Seq 2-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
P02302
Region 1m18 F 2-20 disorder
Region 1m18 F 21-103 order
Region 1m18 B 2-24 disorder
Region 1m18 B 25-103 order
Seq 2-103 Hetero octamer : IID50139 Complex ,
IID50147 Complex ,
Q28D68
Region 3c1c F 2-19 disorder
Region 3c1c F 20-103 order
Region 3c1c B 2-25 disorder
Region 3c1c B 26-103 order
Seq 2-103 Hetero octamer : IID50139 Complex ,
IID50147 Complex ,
Q28D68
Region 3c1b F 2-16 disorder
Region 3c1b F 17-103 order
Region 3c1b B 2-23 disorder
Region 3c1b B 24-103 order
Seq 2-103 Hetero tetramer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 4j8w F 2-16 disorder
Region 4j8w F 17-103 order
Region 4j8w B 2-21 disorder
Region 4j8w B 22-103 order
Region 4j8u F 2-16 disorder
Region 4j8u F 17-103 order
Region 4j8u B 2-21 disorder
Region 4j8u B 22-103 order
Seq 2-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
IID50147 Complex
Region 1p3o F 2-24 disorder
Region 1p3o F 25-103 order
Region 1p3o B 2-21 disorder
Region 1p3o B 22-103 order
Region 1p3k F 2-22 disorder
Region 1p3k F 23-103 order
Region 1p3k B 2-24 disorder
Region 1p3k B 25-103 order
Region 1p3i F 2-24 disorder
Region 1p3i F 25-103 order
Region 1p3i B 2-24 disorder
Region 1p3i B 25-103 order
Region 1p3g F 2-16 disorder
Region 1p3g F 17-103 order
Region 1p3g B 2-24 disorder
Region 1p3g B 25-103 order
Region 1p3a F 2-21 disorder
Region 1p3a F 22-102 order
Region 1p3a F 103-103 disorder
Region 1p3a B 2-24 disorder
Region 1p3a B 25-103 order
Seq 2-103 Hetero trimer : IID00182 Complex ,
IID50147 Complex
Region 2io5 C 2-24 disorder
Region 2io5 C 25-101 order
Region 2io5 C 102-103 disorder
Seq 2-103 Hetero octamer : IID50135 Complex ,
IID50147 Complex ,
Q6AZJ8
Region 3mgq F 2-16 disorder
Region 3mgq F 17-103 order
Region 3mgq B 2-24 disorder
Region 3mgq B 25-103 order
Region 3mgp F 2-16 disorder
Region 3mgp F 17-103 order
Region 3mgp B 2-24 disorder
Region 3mgp B 25-103 order
Seq 2-103 Hetero octamer : IID50135 Complex ,
IID50147 Complex ,
Q6AZJ8
Region 3lel P 2-16 disorder
Region 3lel P 17-103 order
Region 3lel L 2-24 disorder
Region 3lel L 25-103 order
Seq 17-103 Hetero octamer : IID50135 Complex ,
IID50139 Complex ,
P02302
Region 1aoi F 17-103 order
Region 1aoi B 17-20 disorder
Region 1aoi B 21-103 order
Seq 20-103 Hetero nonamer : IID50139 Complex ,
IID50147 Complex
Region 5mlu F 20-25 disorder
Region 5mlu F 26-103 order
Region 5mlu B 20-103 order
Region 4zbj C 21-21 disorder
Region 4zbj C 22-103 order
Seq 21-103 Hetero trimer : IID50147 Complex ,
IID50170 Complex
Region 2hue C 21-102 order
Region 2hue C 103-103 disorder
Region 4eo5 C 21-103 order
48-48 Phosphoserine; by PAK2
92-92 N6-acetyllysine; alternate
13-13 N6-acetyl-N6-methyllysine; alternate
6-6 N6-acetyl-N6-methyllysine; alternate
Function
Function in SwissProt
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.