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IID50149
 UniprotQ10103
ProteinChromo domain-containing protein 1
Genechp1
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
960
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-75 Hetero dimer : IID50143Complex
 Evidence NMR 2rsn A Reference
       Region 2rsn A 1-75 order
       Region 2rsn A 1-15 high_rmsd
Seq 15-75 Hetero dimer : P09988
 Evidence X-RAY 3g7l A Reference
       Region 3g7l A 15-18 disorder
       Region 3g7l A 19-73 order
       Region 3g7l A 74-75 disorder
Seq 504-960 Hetero dimer : O94687,Q12306
 Evidence X-RAY 3tix D Reference
       Region 3tix D 504-513 disorder
       Region 3tix D 514-778 order
       Region 3tix D 779-797 disorder
       Region 3tix D 798-863 order
       Region 3tix D 864-866 disorder
       Region 3tix D 867-959 order
       Region 3tix D 960-960 disorder
Seq 504-960 Hetero dimer : O94687,Q12306
 Evidence X-RAY 3tix B Reference
       Region 3tix B 504-514 disorder
       Region 3tix B 515-777 order
       Region 3tix B 778-798 disorder
       Region 3tix B 799-956 order
       Region 3tix B 957-960 disorder
 
Prediction
NeProc
Disorder 1-20,74-84,131-505
Order 21-73,85-130,506-509,516-581,586-960
ProS 329-338,351-383,412-415,425-445,453-470,476-480,492-505
AlphaFold
Disorder 1-19,126-310,318-322,335-335,343-353,372-372,374-375,382-516,777-799,884-886,960-960
Order 20-125,311-317,323-334,336-342,354-371,373-373,376-381,517-776,800-883,887-959
Pfam Hmmer
PF00385 22-73 2.2e-17
SEG 65-82 ,119-130 ,141-153 ,201-210 ,499-518 ,672-682
Function
Function in SwissProt
Component of the kinetochore which plays a role in stabilizing microtubules and so allowing accurate chromosome segregation. Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. A member of the RNA-induced transcriptional silencing (RITS) complex which is involved in the biosynthesis of dsRNA from primer siRNAs provided by the RNA-directed RNA polymerase (RDRC) complex.