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IID50153
 UniprotQ8K2F0
ProteinBromodomain-containing protein 3
GeneBrd3
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
726
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 24-146 Hetero dimer : IID50040Complex
 Evidence NMR 2l5e A Reference
       Region 2l5e A 24-146 order
Seqphosphorylation
    564-564 Phosphoserine
    280-280 Phosphoserine
    262-262 Phosphoserine
 
Prediction
NeProc
Disorder 1-30,140-306,414-454,483-485,526-578,616-621,626-651,680-726
Order 31-139,307-413,455-482,486-525,579-615,622-625,652-679
ProS 18-30,201-214,250-259,289-294,414-417,547-553,560-563,570-578,616-621,626-638,680-680
AlphaFold
Disorder 1-16,149-305,417-456,479-570,608-609,612-614,640-657,675-726
Order 17-148,306-416,457-478,571-607,610-611,615-639,658-674
Pfam Hmmer
PF00439 38-127 8.1e-44
PF00439 313-402 8.7e-40
SEG 12-32 ,148-179 ,207-236 ,245-269 ,435-459 ,486-541 ,565-569 ,651-674 ,691-726
Function
Function in SwissProt
Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors (PubMed:21536911). Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (PubMed:21536911).