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IID50166
 UniprotP07276
ProteinDNA repair protein RAD2
GeneRAD2
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
1031
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-111,732-986 Homo dimer :
 Evidence X-RAY 4q0r A Reference
       Region 4q0r A 1-38 order
       Region 4q0r A 39-52 disorder
       Region 4q0r A 53-92 order
       Region 4q0r A 93-111 disorder
       Region 4q0r A 732-767 disorder
       Region 4q0r A 768-982 order
       Region 4q0r A 983-986 disorder
 Evidence X-RAY 4q0r B Reference
       Region 4q0r B 1-34 order
       Region 4q0r B 35-52 disorder
       Region 4q0r B 53-87 order
       Region 4q0r B 88-111 disorder
       Region 4q0r B 732-767 disorder
       Region 4q0r B 768-899 order
       Region 4q0r B 900-908 disorder
       Region 4q0r B 909-983 order
       Region 4q0r B 984-986 disorder
Seq 2-111,732-986 Homo dimer :
 Evidence X-RAY 4q0z A Reference
       Region 4q0z A 2-104 order
       Region 4q0z A 105-111 disorder
       Region 4q0z A 765-983 order
       Region 4q0z A 984-986 disorder
 Evidence X-RAY 4q0z B Reference
       Region 4q0z B 2-45 order
       Region 4q0z B 46-47 disorder
       Region 4q0z B 48-90 order
       Region 4q0z B 91-111 disorder
       Region 4q0z B 732-763 disorder
       Region 4q0z B 764-983 order
       Region 4q0z B 984-986 disorder
Seq 2-111,732-986 Homo dimer :
 Evidence X-RAY 4q0w A Reference
       Region 4q0w A 2-45 order
       Region 4q0w A 46-47 disorder
       Region 4q0w A 48-100 order
       Region 4q0w A 101-111 disorder
       Region 4q0w A 732-764 disorder
       Region 4q0w A 765-983 order
       Region 4q0w A 984-986 disorder
 Evidence X-RAY 4q0w B Reference
       Region 4q0w B 2-39 order
       Region 4q0w B 40-49 disorder
       Region 4q0w B 50-93 order
       Region 4q0w B 94-111 disorder
       Region 4q0w B 732-760 disorder
       Region 4q0w B 761-898 order
       Region 4q0w B 899-904 disorder
       Region 4q0w B 905-985 order
       Region 4q0w B 986-986 disorder
Seq 2-111,732-986 Homo dimer :
 Evidence X-RAY 4q10 A Reference
       Region 4q10 A 2-43 order
       Region 4q10 A 44-49 disorder
       Region 4q10 A 50-91 order
       Region 4q10 A 50-90 order
       Region 4q10 A 91-111 disorder
       Region 4q10 A 732-764 disorder
       Region 4q10 A 765-830 order
       Region 4q10 A 831-834 disorder
       Region 4q10 A 835-985 order
       Region 4q10 A 986-986 disorder
 Evidence X-RAY 4q10 B Reference
       Region 4q10 B 2-44 order
       Region 4q10 B 45-48 disorder
       Region 4q10 B 49-89 order
       Region 4q10 B 90-111 disorder
       Region 4q10 B 732-764 disorder
       Region 4q10 B 765-899 order
       Region 4q10 B 900-907 disorder
       Region 4q10 B 908-983 order
       Region 4q10 B 984-986 disorder
Seq 2-111,732-986 Homo dimer :
 Evidence X-RAY 4q0z E Reference
       Region 4q0z E 2-46 order
       Region 4q0z E 47-48 disorder
       Region 4q0z E 49-92 order
       Region 4q0z E 93-111 disorder
       Region 4q0z E 732-764 disorder
       Region 4q0z E 765-900 order
       Region 4q0z E 901-902 disorder
       Region 4q0z E 903-925 order
       Region 4q0z E 926-927 disorder
       Region 4q0z E 928-983 order
       Region 4q0z E 984-986 disorder
 Evidence X-RAY 4q0z F Reference
       Region 4q0z F 2-43 order
       Region 4q0z F 44-48 disorder
       Region 4q0z F 49-94 order
       Region 4q0z F 95-111 disorder
       Region 4q0z F 732-764 disorder
       Region 4q0z F 765-983 order
       Region 4q0z F 984-986 disorder
Seqdisorder 642-690
 Evidence NMR Reference
       Region 642-690 disorder
Seq 642-690 Hetero dimer : IID50021Complex
 Evidence NMR 2lox B Reference
       Region 2lox B 642-660 disorder
       Region 2lox B 661-680 order
       Region 2lox B 661-664 high_rmsd
       Region 2lox B 677-680 high_rmsd
       Region 2lox B 681-690 disorder
SeqProS verified 661-680 Hetero dimer : IID50021Complex
       Region 2lox B 661-680 order
       Region 642-690 disorder
Seqphosphorylation
    118-118 Phosphoserine
    367-367 Phosphoserine
    583-583 Phosphoserine
 
Prediction
NeProc
Disorder 119-187,255-290,296-757,1007-1031
Order 1-118,188-254,291-295,758-902,907-1006
ProS 119-126,134-148,155-187,262-290,296-311,383-396,408-416,547-554,589-592,699-709,716-757,1012-1031
AlphaFold
Disorder 1-1,46-47,116-138,142-143,146-151,153-181,183-184,212-216,254-277,287-288,290-291,294-441,451-452,455-636,638-638,641-641,644-644,646-708,712-712,723-724,726-746,831-832,899-899,901-905,993-1014,1031-1031
Order 2-45,48-115,139-141,144-145,152-152,182-182,185-211,217-253,278-286,289-289,292-293,442-450,453-454,637-637,639-640,642-643,645-645,709-711,713-722,725-725,747-830,833-898,900-900,906-992,1015-1030
Pfam Hmmer
PF00752 1-98 2.1e-57
PF00867 780-868 7.6e-52
SEG 89-100 ,202-214 ,360-374 ,647-661 ,988-997
Function
Function in SwissProt
Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair.