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IID50173
 UniprotP38850
ProteinRegulator of Ty1 transposition protein 107
GeneRTT107
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
1070
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 820-1070 Hetero tetramer : IID50063Complex
 Evidence X-RAY 3t7k B Reference
       Region 3t7k B 820-820 disorder
       Region 3t7k B 821-914 order
       Region 3t7k B 915-921 disorder
       Region 3t7k B 922-1001 order
       Region 3t7k B 1002-1008 disorder
       Region 3t7k B 1009-1068 order
       Region 3t7k B 1069-1070 disorder
 Evidence X-RAY 3t7k A Reference
       Region 3t7k A 820-820 disorder
       Region 3t7k A 821-914 order
       Region 3t7k A 915-921 disorder
       Region 3t7k A 922-1000 order
       Region 3t7k A 1001-1008 disorder
       Region 3t7k A 1009-1068 order
       Region 3t7k A 1069-1070 disorder
Seq 820-1070 Homo dimer :
 Evidence X-RAY 3t7j B Reference
       Region 3t7j B 820-915 order
       Region 3t7j B 916-921 disorder
       Region 3t7j B 922-1001 order
       Region 3t7j B 1002-1008 disorder
       Region 3t7j B 1009-1069 order
       Region 3t7j B 1070-1070 disorder
 Evidence X-RAY 3t7j A Reference
       Region 3t7j A 820-915 order
       Region 3t7j A 916-921 disorder
       Region 3t7j A 922-1001 order
       Region 3t7j A 1002-1008 disorder
       Region 3t7j A 1009-1069 order
       Region 3t7j A 1070-1070 disorder
 Evidence X-RAY 3t7i B Reference
       Region 3t7i B 820-915 order
       Region 3t7i B 916-920 disorder
       Region 3t7i B 921-1000 order
       Region 3t7i B 1001-1008 disorder
       Region 3t7i B 1009-1068 order
       Region 3t7i B 1069-1070 disorder
 Evidence X-RAY 3t7i A Reference
       Region 3t7i A 820-915 order
       Region 3t7i A 916-920 disorder
       Region 3t7i A 921-1000 order
       Region 3t7i A 1001-1008 disorder
       Region 3t7i A 1009-1068 order
       Region 3t7i A 1069-1070 disorder
Seqphosphorylation
    304-304 Phosphoserine
    532-532 Phosphothreonine
    593-593 Phosphoserine
    591-591 Phosphoserine
    720-720 Phosphoserine
    800-800 Phosphoserine
    806-806 Phosphoserine
 
Prediction
NeProc
Disorder 1-4,228-258,492-666,695-831,997-1005,1070-1070
Order 5-227,259-491,667-694,832-996,1006-1069
ProS 228-238,246-258,598-604,615-621,639-643,648-666,695-745,751-754,780-795,997-1005
AlphaFold
Disorder 1-1,183-194,486-815,870-872,916-922,988-990,1002-1008,1070-1070
Order 2-182,195-485,816-869,873-915,923-987,991-1001,1009-1069
Pfam Hmmer
PF00533 2-103 6.5e-06
PF00533 117-213 3.5e-14
PF00533 261-352 1.2e-10
PF00533 370-453 5.6e-11
SEG 184-189 ,661-676
Function
Function in SwissProt
Required for resumption of chromosome replication after DNA damage, specifically in S phase. Is recruited to chromatin in the presence of RTT109 and RTT101 in response to stalled replication forks and acts as a scaffold during DNA repair.