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IID50174
 UniprotP39009
ProteinDNA damage response protein kinase DUN1
GeneDUN1
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
513
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 19-159 Hetero dimer : IID50168Complex
 Evidence NMR 2jql A Reference
       Region 2jql A 19-159 order
       Region 2jql A 19-28 high_rmsd
       Region 2jql A 140-159 high_rmsd
Seq 19-159 Monomer :
 Evidence NMR 2jqj A Reference
       Region 2jqj A 19-159 order
       Region 2jqj A 19-29 high_rmsd
       Region 2jqj A 140-159 high_rmsd
Seqphosphorylation
    139-139 Phosphoserine
    380-380 Phosphothreonine
    10-10 Phosphoserine
 
Prediction
NeProc
Disorder 1-30,142-189,238-240,491-513
Order 31-137,190-237,241-340,348-484
ProS 4-12,238-240,491-513
AlphaFold
Disorder 1-29,140-192,372-384,482-494,497-504,508-508,510-513
Order 30-139,193-371,385-481,495-496,505-507,509-509
Pfam Hmmer
PF00498 56-128 2.8e-13
PF00069 200-480 2.4e-94
SEG 172-184 ,234-244
Function
Function in SwissProt
Transducer of the DNA damage signal. Phosphorylates SML1 on serine residues. Cooperates with the PAN deadenylation complex in the regulation of RAD5 mRNA levels and cell survival in response to replicational stress.