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IID50188
 UniprotQ03041
ProteinCyclic nucleotide-gated olfactory channel
GeneCNGA2
OrganismBos taurus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
663
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 60-85 Hetero dimer : IID50309Complex
 Evidence NMR 1sy9 B Reference
       Region 1sy9 B 60-63 disorder
       Region 1sy9 B 64-82 order
       Region 1sy9 B 83-85 disorder
 
Prediction
NeProc
Disorder 1-125,647-663
Order 126-646
ProS 1-10,52-55,65-83,92-100,116-125
AlphaFold
Disorder 1-68,71-71,80-130,422-422,454-454,528-529,587-594,644-663
Order 69-70,72-79,131-421,423-453,455-527,530-586,595-643
Pfam Hmmer
PF00520 177-371 5.7e-30
PF00027 472-565 1.4e-21
SEG 12-23 ,111-127 ,278-286
Function
Function in SwissProt
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.