Search Keyword:


Search option:


IID50202
 UniprotP21674
ProteinFollistatin
GeneFst
OrganismRattus norvegicus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
344
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 93-165 Monomer :
 Evidence X-RAY 1lr9 A Reference
       Region 1lr9 A 93-165 order
 Evidence X-RAY 1lr8 A Reference
       Region 1lr8 A 93-165 order
 Evidence X-RAY 1lr7 A Reference
       Region 1lr7 A 93-165 order
Seq 93-241 Hetero tetramer : IID00338Complex
 Evidence X-RAY 2arp F Reference
       Region 2arp F 93-93 disorder
       Region 2arp F 94-241 order
 
Prediction
NeProc
Disorder 1-16,319-344
Order 17-318
ProS 1-16,319-344
AlphaFold
Disorder 1-28,277-279,319-344
Order 29-276,280-318
Pfam Hmmer
PF00050 118-164 4.5e-17
PF00050 192-239 1.5e-15
PF00050 270-316 3.2e-18
SEG 11-19 ,321-330
Function
Function in SwissProt
Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).