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IID50228
 UniprotQ61066
ProteinNuclear receptor subfamily 0 group B member 1
GeneNr0b1
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
472
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 205-472 Hetero trimer : IID50211Complex
 Evidence X-RAY 3f5c C Reference
       Region 3f5c C 205-251 disorder
       Region 3f5c C 252-312 order
       Region 3f5c C 313-352 disorder
       Region 3f5c C 353-472 order
 Evidence X-RAY 3f5c B Reference
       Region 3f5c B 205-250 disorder
       Region 3f5c B 251-313 order
       Region 3f5c B 314-352 disorder
       Region 3f5c B 353-472 order
 
Prediction
NeProc
Disorder 1-6,13-62,68-128,155-246,324-353
Order 7-12,63-67,129-154,247-323,354-472
ProS 1-6,13-17,33-45,50-56,68-72,78-84,114-120,155-206,213-219
AlphaFold
Disorder 1-247,312-355,421-422,471-472
Order 248-311,356-420,423-470
Pfam Hmmer
PF00104 261-467 1.2e-35
SEG 328-345
Function
Function in SwissProt
Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).