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IID50233
 UniprotQ8CF89
ProteinTGF-beta-activated kinase 1 and MAP3K7-binding protein 1
GeneTab1
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
502
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 384-412 Hetero dimer : IID50045Complex
 Evidence X-RAY 4loq N Reference
       Region 4loq N 384-384 disorder
       Region 4loq N 385-394 order
       Region 4loq N 395-403 disorder
       Region 4loq N 404-411 order
       Region 4loq N 412-412 disorder
 Evidence X-RAY 4loq K Reference
       Region 4loq K 384-395 order
       Region 4loq K 396-402 disorder
       Region 4loq K 403-412 order
 Evidence X-RAY 4loq L Reference
       Region 4loq L 384-395 order
       Region 4loq L 396-402 disorder
       Region 4loq L 403-412 order
 Evidence X-RAY 4loq M Reference
       Region 4loq M 384-384 disorder
       Region 4loq M 385-394 order
       Region 4loq M 395-403 disorder
       Region 4loq M 404-411 order
       Region 4loq M 412-412 disorder
 Evidence X-RAY 4lop N Reference
       Region 4lop N 384-394 order
       Region 4lop N 395-403 disorder
       Region 4lop N 404-411 order
       Region 4lop N 412-412 disorder
 Evidence X-RAY 4lop K Reference
       Region 4lop K 384-395 order
       Region 4lop K 396-403 disorder
       Region 4lop K 404-412 order
 Evidence X-RAY 4lop L Reference
       Region 4lop L 384-395 order
       Region 4lop L 396-403 disorder
       Region 4lop L 404-412 order
 Evidence X-RAY 4lop M Reference
       Region 4lop M 384-384 disorder
       Region 4lop M 385-394 order
       Region 4lop M 395-403 disorder
       Region 4lop M 404-411 order
       Region 4lop M 412-412 disorder
 Evidence X-RAY 4loo B Reference
       Region 4loo B 384-395 order
       Region 4loo B 396-402 disorder
       Region 4loo B 403-411 order
       Region 4loo B 412-412 disorder
Seqphosphorylation
    440-440 Phosphothreonine
    436-436 Phosphoserine
    429-429 Phosphothreonine
    421-421 Phosphoserine
    7-7 Phosphoserine
 
Prediction
NeProc
Disorder 1-17,135-152,371-471,493-502
Order 18-134,153-370,472-492
ProS 1-8,14-17,135-152,385-392,435-439,443-448,471-471,493-498
AlphaFold
Disorder 1-15,372-472,474-478,492-502
Order 16-371,473-473,479-491
Pfam Hmmer
PF00481 69-334 2.8e-57
SEG 397-408 ,438-455
Function
Function in SwissProt
May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.