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IID50234
 UniprotQ9DCR4
ProteinEP300-interacting inhibitor of differentiation 1
GeneEid1
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
169
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 91-106 Hetero dimer : IID50230Complex,IID90020Complex
 Evidence X-RAY 4nuf P Reference
       Region 4nuf P 91-106 order
 
Prediction
NeProc
Disorder 1-80,167-169
Order 81-166
ProS 4-16,21-26,58-80
AlphaFold
Disorder 1-3,6-92,94-94,108-125,151-169
Order 4-5,93-93,95-107,126-150
SEG 31-58 ,66-85 ,158-169
Function
Function in SwissProt
Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.