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IID50245
 UniprotQ09683
ProteinDNA repair protein rad32
Generad32
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
649
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 7-413 Hetero dimer : IID50239Complex
 Evidence X-RAY 4fbw B Reference
       Region 4fbw B 7-13 disorder
       Region 4fbw B 14-101 order
       Region 4fbw B 102-109 disorder
       Region 4fbw B 110-136 order
       Region 4fbw B 137-141 disorder
       Region 4fbw B 142-412 order
       Region 4fbw B 413-413 disorder
Seq 7-413 Hetero dimer : IID50239Complex
 Evidence X-RAY 4fbw A Reference
       Region 4fbw A 7-13 disorder
       Region 4fbw A 14-100 order
       Region 4fbw A 101-112 disorder
       Region 4fbw A 113-136 order
       Region 4fbw A 137-141 disorder
       Region 4fbw A 142-162 order
       Region 4fbw A 163-165 disorder
       Region 4fbw A 166-412 order
       Region 4fbw A 413-413 disorder
Seq 15-413 Homo dimer :
 Evidence X-RAY 4fcx B Reference
       Region 4fcx B 15-100 order
       Region 4fcx B 101-110 disorder
       Region 4fcx B 111-135 order
       Region 4fcx B 136-141 disorder
       Region 4fcx B 142-323 order
       Region 4fcx B 324-328 disorder
       Region 4fcx B 329-358 order
       Region 4fcx B 359-366 disorder
       Region 4fcx B 367-411 order
       Region 4fcx B 412-413 disorder
 Evidence X-RAY 4fcx A Reference
       Region 4fcx A 15-100 order
       Region 4fcx A 101-116 disorder
       Region 4fcx A 117-133 order
       Region 4fcx A 134-142 disorder
       Region 4fcx A 143-359 order
       Region 4fcx A 360-367 disorder
       Region 4fcx A 368-411 order
       Region 4fcx A 412-413 disorder
Seq 15-413 Monomer : IID50239Complex
 Evidence X-RAY 4fbk A Reference
       Region 4fbk A 15-102 order
       Region 4fbk A 103-107 disorder
       Region 4fbk A 108-139 order
       Region 4fbk A 140-141 disorder
       Region 4fbk A 142-413 order
 Evidence X-RAY 4fbk B Reference
       Region 4fbk B 15-100 order
       Region 4fbk B 101-110 disorder
       Region 4fbk B 111-138 order
       Region 4fbk B 139-140 disorder
       Region 4fbk B 141-413 order
Seq 15-413 Monomer : IID50239Complex
 Evidence X-RAY 4fbq A Reference
       Region 4fbq A 15-102 order
       Region 4fbq A 103-108 disorder
       Region 4fbq A 109-136 order
       Region 4fbq A 137-141 disorder
       Region 4fbq A 142-164 order
       Region 4fbq A 165-165 disorder
       Region 4fbq A 166-413 order
 Evidence X-RAY 4fbq B Reference
       Region 4fbq B 15-100 order
       Region 4fbq B 101-109 disorder
       Region 4fbq B 110-136 order
       Region 4fbq B 137-140 disorder
       Region 4fbq B 141-412 order
       Region 4fbq B 413-413 disorder
 
Prediction
NeProc
Disorder 1-12,415-430,505-649
Order 13-362,368-414,431-504
ProS 505-524,636-639,646-649
AlphaFold
Disorder 1-13,102-107,109-109,140-140,414-441,443-443,449-454,509-649
Order 14-101,108-108,110-139,141-413,442-442,444-448,455-508
Pfam Hmmer
PF00149 18-254 1e-24
PF04152 255-467 2.2e-134
SEG 95-109
Function
Function in SwissProt
Required for the repair of double strand breaks (DSB) caused by gamma and UV radiation. May work in conjunction with rhp51.
Biological Process
See also
Diagram with PDB data
nbs1/rad32Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site