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IID50248
 UniprotO35627
ProteinNuclear receptor subfamily 1 group I member 3
GeneNr1i3
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
358
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 109-358 Homo dimer :
 Evidence X-RAY 1xnx B Reference
       Region 1xnx B 109-119 disorder
       Region 1xnx B 120-343 order
       Region 1xnx B 344-349 disorder
       Region 1xnx B 350-357 order
       Region 1xnx B 358-358 disorder
 Evidence X-RAY 1xnx A Reference
       Region 1xnx A 109-113 disorder
       Region 1xnx A 114-345 order
       Region 1xnx A 346-358 disorder
Seq 117-358 Hetero tetramer : IID00031Complex,IID50249Complex
 Evidence X-RAY 1xls H Reference
       Region 1xls H 117-358 order
 Evidence X-RAY 1xls G Reference
       Region 1xls G 117-358 order
 Evidence X-RAY 1xls F Reference
       Region 1xls F 117-358 order
 Evidence X-RAY 1xls E Reference
       Region 1xls E 117-358 order
Seqphosphorylation
    48-48 Phosphothreonine; by PKC
 
Prediction
NeProc
Disorder 1-17,154-162
Order 18-149,163-358
AlphaFold
Disorder 1-17,156-160,310-315
Order 18-155,161-309,316-358
Pfam Hmmer
PF00105 19-94 1.3e-39
PF00104 176-356 3e-34
SEG 94-110
Function
Function in SwissProt
Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (By similarity).