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IID50250
 UniprotP20153
ProteinProtein ultraspiracle
Geneusp
OrganismDrosophila melanogaster
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
508
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 94-179 Hetero dimer : IID50251Complex
 Evidence X-RAY 1r0o A Reference
       Region 1r0o A 94-101 disorder
       Region 1r0o A 102-177 order
       Region 1r0o A 178-179 disorder
 Evidence X-RAY 2han A Reference
       Region 2han A 94-100 disorder
       Region 2han A 101-178 order
       Region 2han A 179-179 disorder
Seq 230-508 Homo trimer :
 Evidence X-RAY 1hg4 F Reference
       Region 1hg4 F 230-237 disorder
       Region 1hg4 F 238-334 order
       Region 1hg4 F 335-359 disorder
       Region 1hg4 F 360-502 order
       Region 1hg4 F 503-508 disorder
 Evidence X-RAY 1hg4 E Reference
       Region 1hg4 E 230-237 disorder
       Region 1hg4 E 238-334 order
       Region 1hg4 E 335-359 disorder
       Region 1hg4 E 360-502 order
       Region 1hg4 E 503-508 disorder
 Evidence X-RAY 1hg4 B Reference
       Region 1hg4 B 230-237 disorder
       Region 1hg4 B 238-334 order
       Region 1hg4 B 335-359 disorder
       Region 1hg4 B 360-502 order
       Region 1hg4 B 503-508 disorder
 Evidence X-RAY 1hg4 D Reference
       Region 1hg4 D 230-237 disorder
       Region 1hg4 D 238-334 order
       Region 1hg4 D 335-361 disorder
       Region 1hg4 D 362-502 order
       Region 1hg4 D 503-508 disorder
 Evidence X-RAY 1hg4 C Reference
       Region 1hg4 C 230-237 disorder
       Region 1hg4 C 238-334 order
       Region 1hg4 C 335-361 disorder
       Region 1hg4 C 362-502 order
       Region 1hg4 C 503-508 disorder
 Evidence X-RAY 1hg4 A Reference
       Region 1hg4 A 230-237 disorder
       Region 1hg4 A 238-334 order
       Region 1hg4 A 335-359 disorder
       Region 1hg4 A 360-502 order
       Region 1hg4 A 503-508 disorder
Seqphosphorylation
    35-35 Phosphoserine
 
Prediction
NeProc
Disorder 1-101,180-276,341-364,501-508
Order 102-179,277-336,365-500
ProS 1-23,180-183,237-251,259-264,359-364,501-508
AlphaFold
Disorder 1-101,179-236,336-359,504-508
Order 102-178,237-335,360-503
Pfam Hmmer
PF00105 102-177 1.2e-50
PF00104 286-494 1.7e-57
SEG 57-67 ,73-90 ,150-164 ,190-226 ,240-251 ,335-350
Function
Function in SwissProt
Receptor for ecdysone. May be an important modulator of insect metamorphosis. Plays an important part in embryonic and post-embryonic development. Binds to ecdysone response elements (ECRES) such as in the promoter region of s15 chorion gene.