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IID50252
UniprotP04625
ProteinThyroid hormone receptor alpha
GeneTHRA
OrganismGallus gallus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
408
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 148-408 Hetero dimer : IID00031Complex
 Evidence X-RAY 3uvv A Reference
       Region 3uvv A 148-194 order
       Region 3uvv A 195-202 disorder
       Region 3uvv A 203-204 order
       Region 3uvv A 205-205 disorder
       Region 3uvv A 206-405 order
       Region 3uvv A 406-408 disorder
Seqphosphorylation
    28-28 Phosphoserine
    12-12 Phosphoserine; by CK2
 
Prediction
NeProc
Disorder 1-47,156-162,193-209
Order 48-155,163-192,210-408
ProS 193-198
AlphaFold
Disorder 1-39,197-205,406-408
Order 40-196,206-405
Pfam Hmmer
PF00105 49-126 7.2e-52
PF00104 221-402 1.7e-42
SEG 132-147
Function
Function in SwissProt
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.