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IID50259
 UniprotP87314
ProteinProtein hir1
Genehip1
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
932
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 469-497 Hetero tetramer : IID50258Complex
 Evidence X-RAY 2z34 C Reference
       Region 2z34 C 469-473 disorder
       Region 2z34 C 474-494 order
       Region 2z34 C 495-497 disorder
 Evidence X-RAY 2z34 D Reference
       Region 2z34 D 469-474 disorder
       Region 2z34 D 475-496 order
       Region 2z34 D 497-497 disorder
 
Prediction
NeProc
Disorder 377-587,721-727,792-829,929-932
Order 1-53,59-107,114-376,588-720,728-791,830-928
ProS 377-387,399-402,477-482,522-527,792-819
AlphaFold
Disorder 54-61,106-119,375-385,398-479,483-584,599-601,614-614,718-733,784-795,892-894,931-932
Order 1-53,62-105,120-374,386-397,480-482,585-598,602-613,615-717,734-783,796-891,895-930
Pfam Hmmer
PF00400 8-46 6.7e-09
PF00400 64-102 2.9e-11
PF00400 124-162 8.3e-07
PF00400 166-204 1.4e-08
PF00400 260-307 3.5e-05
PF07569 663-886 1.8e-123
SEG 51-61 ,491-507 ,514-525 ,568-584
Function
Function in SwissProt
Probably required for replication-independent chromatin assembly. Required for transcriptional silencing in the outer repeat (otr) centromeric repeats and the Tf2 long terminal repeat retrotransposons. Repressor of histone gene transcription in G1 arrested cells. Required for repression of htb1 gene expression outside of S phase.