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IID50276
UniprotP40517
ProteinRan-specific GTPase-activating protein 2
GeneYRB2
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
327
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 90-327 Hetero trimer : E7KFU1,IID50169Complex
 Evidence X-RAY 3wyf B Reference
       Region 3wyf B 90-96 disorder
       Region 3wyf B 97-110 order
       Region 3wyf B 111-140 disorder
       Region 3wyf B 141-155 order
       Region 3wyf B 156-199 disorder
       Region 3wyf B 200-227 order
       Region 3wyf B 228-229 disorder
       Region 3wyf B 230-247 order
       Region 3wyf B 248-250 disorder
       Region 3wyf B 251-296 order
       Region 3wyf B 297-301 disorder
       Region 3wyf B 302-308 order
       Region 3wyf B 309-309 disorder
       Region 3wyf B 310-325 order
       Region 3wyf B 326-327 disorder
 Evidence X-RAY 3wyf E Reference
       Region 3wyf E 90-96 disorder
       Region 3wyf E 97-110 order
       Region 3wyf E 111-140 disorder
       Region 3wyf E 141-155 order
       Region 3wyf E 156-199 disorder
       Region 3wyf E 200-227 order
       Region 3wyf E 228-229 disorder
       Region 3wyf E 230-247 order
       Region 3wyf E 248-250 disorder
       Region 3wyf E 251-271 order
       Region 3wyf E 272-274 disorder
       Region 3wyf E 275-297 order
       Region 3wyf E 298-301 disorder
       Region 3wyf E 302-324 order
       Region 3wyf E 325-327 disorder
SeqProS predicted 97-155 The unbound state of this region is predicted to be disordered by DICHOT, FoldIndex and MobiDB. Hetero trimer : E7KFU1,IID50169Complex
       Region 3wyf B 97-110 order
       Region 3wyf B 141-155 order
       Region 3wyf E 97-110 order
       Region 3wyf E 141-155 order
Seqphosphorylation
    31-31 Phosphothreonine
    179-179 Phosphoserine
 
Prediction
NeProc
Disorder 1-211
Order 212-327
ProS 191-211
AlphaFold
Disorder 1-94,108-138,157-193
Order 95-107,139-156,194-327
Pfam Hmmer
PF00638 204-327 1.1e-75
SEG 55-70 ,140-152 ,189-206
Function
Function in SwissProt
Important for the export of protein containing nuclear export signal (NES) out of the nucleus. Stimulates the GTPase activity of GSP1.