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IID50302
 UniprotO43044
ProteinNucleoporin nup120
Genenup120
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
1136
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-1136 Hetero dimer : IID50301Complex
 Evidence X-RAY 4gq2 M Reference
       Region 4gq2 M 1-34 order
       Region 4gq2 M 35-43 disorder
       Region 4gq2 M 44-219 order
       Region 4gq2 M 220-226 disorder
       Region 4gq2 M 227-317 order
       Region 4gq2 M 318-320 disorder
       Region 4gq2 M 321-384 order
       Region 4gq2 M 385-387 disorder
       Region 4gq2 M 388-398 order
       Region 4gq2 M 399-404 disorder
       Region 4gq2 M 405-445 order
       Region 4gq2 M 446-450 disorder
       Region 4gq2 M 451-745 order
       Region 4gq2 M 746-758 disorder
       Region 4gq2 M 759-949 order
 Evidence X-RAY 4fhn D Reference
       Region 4fhn D 1-29 order
       Region 4fhn D 30-48 disorder
       Region 4fhn D 49-208 order
       Region 4fhn D 209-232 disorder
       Region 4fhn D 233-397 order
       Region 4fhn D 398-403 disorder
       Region 4fhn D 404-445 order
       Region 4fhn D 446-449 disorder
       Region 4fhn D 450-555 order
       Region 4fhn D 556-572 disorder
       Region 4fhn D 573-657 order
       Region 4fhn D 658-662 disorder
       Region 4fhn D 663-745 order
       Region 4fhn D 746-757 disorder
       Region 4fhn D 758-777 order
       Region 4fhn D 778-786 disorder
       Region 4fhn D 787-866 order
       Region 4fhn D 867-894 disorder
       Region 4fhn D 895-923 order
       Region 4fhn D 924-927 disorder
       Region 4fhn D 928-1052 order
       Region 4fhn D 1053-1054 disorder
       Region 4fhn D 1055-1080 order
       Region 4fhn D 1081-1100 disorder
       Region 4fhn D 1101-1127 order
       Region 4fhn D 1128-1136 disorder
 Evidence X-RAY 4fhn B Reference
       Region 4fhn B 1-26 order
       Region 4fhn B 27-49 disorder
       Region 4fhn B 50-208 order
       Region 4fhn B 209-229 disorder
       Region 4fhn B 230-555 order
       Region 4fhn B 556-569 disorder
       Region 4fhn B 570-657 order
       Region 4fhn B 658-662 disorder
       Region 4fhn B 663-739 order
       Region 4fhn B 740-757 disorder
       Region 4fhn B 758-777 order
       Region 4fhn B 778-786 disorder
       Region 4fhn B 787-1085 order
       Region 4fhn B 1086-1100 disorder
       Region 4fhn B 1101-1127 order
       Region 4fhn B 1128-1136 disorder
 Evidence X-RAY 4fhm B Reference
       Region 4fhm B 1-33 order
       Region 4fhm B 34-48 disorder
       Region 4fhm B 49-212 order
       Region 4fhm B 213-218 disorder
       Region 4fhm B 219-562 order
       Region 4fhm B 563-569 disorder
       Region 4fhm B 570-750 order
       Region 4fhm B 751-757 disorder
       Region 4fhm B 758-777 order
       Region 4fhm B 778-783 disorder
       Region 4fhm B 784-961 order
 
Prediction
NeProc
Disorder 29-44,214-230,406-411,660-668,748-768,1089-1096
Order 1-28,45-213,231-279,284-405,412-449,460-659,669-740,769-782,787-887,894-1088,1101-1136
ProS 214-230,660-664,751-768
AlphaFold
Disorder 10-19,30-47,49-50,65-70,91-99,121-123,199-203,210-232,275-285,289-293,303-306,316-316,318-319,327-330,337-340,355-358,384-386,398-415,428-431,445-461,553-556,558-559,562-570,606-609,658-671,705-715,737-786,804-809,867-876,890-894,962-964,966-966,983-983,986-986,991-995,1010-1017,1050-1058,1079-1079,1081-1081,1085-1102,1127-1136
Order 1-9,20-29,48-48,51-64,71-90,100-120,124-198,204-209,233-274,286-288,294-302,307-315,317-317,320-326,331-336,341-354,359-383,387-397,416-427,432-444,462-552,557-557,560-561,571-605,610-657,672-704,716-736,787-803,810-866,877-889,895-961,965-965,967-982,984-985,987-990,996-1009,1018-1049,1059-1078,1080-1080,1082-1084,1103-1126
SEG 212-224
Function
Function in SwissProt
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.