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IID50303
 UniprotO54918
ProteinBcl-2-like protein 11
GeneBcl2l11
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
196
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 98-169
 Evidence CD Reference
       Region 98-169 disorder
Seq 139-171 Hetero dimer : IID50336Complex
 Evidence X-RAY 1pq1 B Reference
       Region 1pq1 B 139-171 order
SeqProS verified 139-171 Hetero dimer : IID50336Complex
       Region 1pq1 B 139-171 order
       Region 98-169 disorder
Seqphosphorylation
    90-90 Phosphoserine
    83-83 Phosphoserine
    73-73 Phosphoserine
    65-65 Phosphoserine; by MAPK
 
Prediction
NeProc
Disorder 1-132
Order 133-196
ProS 9-20,64-79,91-110,118-132
AlphaFold
Disorder 1-4,6-61,63-105,107-110,131-140,166-179
Order 5-5,62-62,106-106,111-130,141-165,180-196
Pfam Hmmer
PF06773 1-40 1.2e-29
SEG 80-90
Function
Function in SwissProt
Induces apoptosis and anoikis. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent.