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IID50310
 UniprotP16554
ProteinProtein numb
Genenumb
OrganismDrosophila melanogaster
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
556
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 58-205 Hetero dimer :
 Evidence NMR 2nmb A Reference
       Region 2nmb A 58-63 disorder
       Region 2nmb A 64-205 order
       Region 2nmb A 64-64 high_rmsd
Seq 67-201 Hetero dimer :
 Evidence NMR 1ddm A Reference
       Region 1ddm A 67-201 order
Seqphosphorylation
    430-430 Phosphothreonine
    543-543 Phosphoserine
    537-537 Phosphoserine
 
Prediction
NeProc
Disorder 1-67,208-556
Order 68-207
ProS 10-34,41-61,266-292,298-308,316-319,362-374,501-512,538-543,551-556
AlphaFold
Disorder 1-41,43-43,49-66,209-211,227-232,235-267,270-273,276-276,279-305,322-361,377-377,379-556
Order 42-42,44-48,67-208,212-226,233-234,268-269,274-275,277-278,306-321,362-376,378-378
Pfam Hmmer
PF00640 83-205 4.1e-51
PF06311 206-338 2.5e-77
SEG 43-59 ,251-262 ,345-364 ,391-403 ,489-500
Function
Function in SwissProt
Required in determination of cell fate during sensory organ formation in embryos (PubMed:2752427). Restricts developmental potential and promote maturation of intermediary neuronal progenitor (INP) cells probably acting as an antagonist of Notch signaling (PubMed:24550111, PubMed:28899667, PubMed:18342578).