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IID50315
UniprotP35127
ProteinUbiquitin carboxyl-terminal hydrolase YUH1
GeneYUH1
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
236
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-235 Hetero trimer : P0CG48
 Evidence X-RAY 1cmx C Reference
       Region 1cmx C 1-6 disorder
       Region 1cmx C 7-60 order
       Region 1cmx C 61-78 disorder
       Region 1cmx C 79-234 order
       Region 1cmx C 235-235 disorder
 Evidence X-RAY 1cmx A Reference
       Region 1cmx A 1-5 disorder
       Region 1cmx A 6-62 order
       Region 1cmx A 63-77 disorder
       Region 1cmx A 78-234 order
       Region 1cmx A 235-235 disorder
 
Prediction
NeProc
Disorder 1-4
Order 5-236
AlphaFold
Disorder 1-5,63-69,74-75,121-125,236-236
Order 6-62,70-73,76-120,126-235
Pfam Hmmer
PF01088 7-218 3.5e-94
Function
Function in SwissProt
Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or RUB1. Preferentially cleaves ubiquitin from peptides and small adducts.