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IID50319
 UniprotP46673
ProteinNucleoporin NUP85
GeneNUP85
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
744
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-564 Hetero dimer : P53011
 Evidence X-RAY 3ewe D Reference
       Region 3ewe D 1-64 disorder
       Region 3ewe D 65-83 order
       Region 3ewe D 84-86 disorder
       Region 3ewe D 87-120 order
       Region 3ewe D 121-137 disorder
       Region 3ewe D 138-164 order
       Region 3ewe D 165-168 disorder
       Region 3ewe D 169-192 order
       Region 3ewe D 193-199 disorder
       Region 3ewe D 200-227 order
       Region 3ewe D 228-240 disorder
       Region 3ewe D 241-271 order
       Region 3ewe D 272-277 disorder
       Region 3ewe D 278-292 order
       Region 3ewe D 293-301 disorder
       Region 3ewe D 302-317 order
       Region 3ewe D 318-324 disorder
       Region 3ewe D 325-428 order
       Region 3ewe D 429-453 disorder
       Region 3ewe D 454-490 order
       Region 3ewe D 491-495 disorder
       Region 3ewe D 496-555 order
       Region 3ewe D 556-564 disorder
 Evidence X-RAY 3ewe B Reference
       Region 3ewe B 1-64 disorder
       Region 3ewe B 65-83 order
       Region 3ewe B 84-86 disorder
       Region 3ewe B 87-120 order
       Region 3ewe B 121-137 disorder
       Region 3ewe B 138-164 order
       Region 3ewe B 165-168 disorder
       Region 3ewe B 169-192 order
       Region 3ewe B 193-199 disorder
       Region 3ewe B 200-227 order
       Region 3ewe B 228-240 disorder
       Region 3ewe B 241-271 order
       Region 3ewe B 272-277 disorder
       Region 3ewe B 278-292 order
       Region 3ewe B 293-301 disorder
       Region 3ewe B 302-317 order
       Region 3ewe B 318-324 disorder
       Region 3ewe B 325-428 order
       Region 3ewe B 429-453 disorder
       Region 3ewe B 454-490 order
       Region 3ewe B 491-495 disorder
       Region 3ewe B 496-555 order
       Region 3ewe B 556-564 disorder
Seq 1-570 Hetero octamer : P53011
 Evidence X-RAY 3f3g H Reference
       Region 3f3g H 1-38 disorder
       Region 3f3g H 39-126 order
       Region 3f3g H 127-135 disorder
       Region 3f3g H 136-430 order
       Region 3f3g H 431-451 disorder
       Region 3f3g H 452-561 order
       Region 3f3g H 562-570 disorder
 Evidence X-RAY 3f3g G Reference
       Region 3f3g G 1-38 disorder
       Region 3f3g G 39-126 order
       Region 3f3g G 127-135 disorder
       Region 3f3g G 136-229 order
       Region 3f3g G 230-234 disorder
       Region 3f3g G 235-430 order
       Region 3f3g G 431-450 disorder
       Region 3f3g G 451-554 order
       Region 3f3g G 555-570 disorder
 Evidence X-RAY 3f3g D Reference
       Region 3f3g D 1-38 disorder
       Region 3f3g D 39-126 order
       Region 3f3g D 127-135 disorder
       Region 3f3g D 136-229 order
       Region 3f3g D 230-235 disorder
       Region 3f3g D 236-430 order
       Region 3f3g D 431-451 disorder
       Region 3f3g D 452-554 order
       Region 3f3g D 555-570 disorder
 Evidence X-RAY 3f3g C Reference
       Region 3f3g C 1-39 disorder
       Region 3f3g C 40-126 order
       Region 3f3g C 127-135 disorder
       Region 3f3g C 136-430 order
       Region 3f3g C 431-451 disorder
       Region 3f3g C 452-561 order
       Region 3f3g C 562-570 disorder
 Evidence X-RAY 3f3f H Reference
       Region 3f3f H 1-44 disorder
       Region 3f3f H 45-126 order
       Region 3f3f H 127-131 disorder
       Region 3f3f H 132-440 order
       Region 3f3f H 441-449 disorder
       Region 3f3f H 450-545 order
       Region 3f3f H 546-570 disorder
 Evidence X-RAY 3f3f G Reference
       Region 3f3f G 1-60 disorder
       Region 3f3f G 61-126 order
       Region 3f3f G 127-132 disorder
       Region 3f3f G 133-233 order
       Region 3f3f G 234-234 disorder
       Region 3f3f G 235-441 order
       Region 3f3f G 442-449 disorder
       Region 3f3f G 450-551 order
       Region 3f3f G 552-570 disorder
 Evidence X-RAY 3f3f D Reference
       Region 3f3f D 1-43 disorder
       Region 3f3f D 44-126 order
       Region 3f3f D 127-132 disorder
       Region 3f3f D 133-441 order
       Region 3f3f D 442-446 disorder
       Region 3f3f D 447-549 order
       Region 3f3f D 550-570 disorder
 Evidence X-RAY 3f3f C Reference
       Region 3f3f C 1-46 disorder
       Region 3f3f C 47-126 order
       Region 3f3f C 127-131 disorder
       Region 3f3f C 132-230 order
       Region 3f3f C 231-234 disorder
       Region 3f3f C 235-436 order
       Region 3f3f C 437-450 disorder
       Region 3f3f C 451-544 order
       Region 3f3f C 545-570 disorder
Seq 1-570 Hetero tetramer : P53011
 Evidence X-RAY 3f3p L Reference
       Region 3f3p L 1-37 disorder
       Region 3f3p L 38-126 order
       Region 3f3p L 127-132 disorder
       Region 3f3p L 133-231 order
       Region 3f3p L 232-237 disorder
       Region 3f3p L 238-436 order
       Region 3f3p L 437-450 disorder
       Region 3f3p L 451-545 order
       Region 3f3p L 546-570 disorder
 Evidence X-RAY 3f3p K Reference
       Region 3f3p K 1-38 disorder
       Region 3f3p K 39-126 order
       Region 3f3p K 127-132 disorder
       Region 3f3p K 133-230 order
       Region 3f3p K 231-236 disorder
       Region 3f3p K 237-435 order
       Region 3f3p K 436-449 disorder
       Region 3f3p K 450-551 order
       Region 3f3p K 552-570 disorder
 Evidence X-RAY 3f3p H Reference
       Region 3f3p H 1-38 disorder
       Region 3f3p H 39-126 order
       Region 3f3p H 127-132 disorder
       Region 3f3p H 133-230 order
       Region 3f3p H 231-235 disorder
       Region 3f3p H 236-437 order
       Region 3f3p H 438-450 disorder
       Region 3f3p H 451-548 order
       Region 3f3p H 549-570 disorder
 Evidence X-RAY 3f3p G Reference
       Region 3f3p G 1-38 disorder
       Region 3f3p G 39-125 order
       Region 3f3p G 126-132 disorder
       Region 3f3p G 133-230 order
       Region 3f3p G 231-237 disorder
       Region 3f3p G 238-437 order
       Region 3f3p G 438-450 disorder
       Region 3f3p G 451-548 order
       Region 3f3p G 549-570 disorder
 Evidence X-RAY 3f3p D Reference
       Region 3f3p D 1-43 disorder
       Region 3f3p D 44-126 order
       Region 3f3p D 127-133 disorder
       Region 3f3p D 134-229 order
       Region 3f3p D 230-237 disorder
       Region 3f3p D 238-435 order
       Region 3f3p D 436-449 disorder
       Region 3f3p D 450-550 order
       Region 3f3p D 551-570 disorder
 Evidence X-RAY 3f3p C Reference
       Region 3f3p C 1-38 disorder
       Region 3f3p C 39-125 order
       Region 3f3p C 126-132 disorder
       Region 3f3p C 133-230 order
       Region 3f3p C 231-237 disorder
       Region 3f3p C 238-435 order
       Region 3f3p C 436-450 disorder
       Region 3f3p C 451-547 order
       Region 3f3p C 548-570 disorder
Seq 44-744 Hetero octamer : P35729,P49687,P53011
 Evidence X-RAY 4xmm D Reference
       Region 4xmm D 44-46 disorder
       Region 4xmm D 47-126 order
       Region 4xmm D 127-131 disorder
       Region 4xmm D 132-230 order
       Region 4xmm D 231-234 disorder
       Region 4xmm D 235-436 order
       Region 4xmm D 437-450 disorder
       Region 4xmm D 451-544 order
       Region 4xmm D 545-552 disorder
       Region 4xmm D 553-560 order
       Region 4xmm D 561-566 disorder
       Region 4xmm D 567-585 order
       Region 4xmm D 586-589 disorder
       Region 4xmm D 590-597 order
       Region 4xmm D 598-602 disorder
       Region 4xmm D 603-612 order
       Region 4xmm D 613-615 disorder
       Region 4xmm D 616-634 order
       Region 4xmm D 635-637 disorder
       Region 4xmm D 638-655 order
       Region 4xmm D 656-660 disorder
       Region 4xmm D 661-675 order
       Region 4xmm D 676-684 disorder
       Region 4xmm D 685-699 order
       Region 4xmm D 700-706 disorder
       Region 4xmm D 707-719 order
       Region 4xmm D 720-724 disorder
       Region 4xmm D 725-744 order
Seq 73-743 Hetero heptamer : P35729
 Evidence X-RAY 4xmn D Reference
       Region 4xmn D 73-552 disorder
       Region 4xmn D 553-560 order
       Region 4xmn D 561-566 disorder
       Region 4xmn D 567-585 order
       Region 4xmn D 586-589 disorder
       Region 4xmn D 590-597 order
       Region 4xmn D 598-602 disorder
       Region 4xmn D 603-610 order
       Region 4xmn D 611-615 disorder
       Region 4xmn D 616-634 order
       Region 4xmn D 635-637 disorder
       Region 4xmn D 638-655 order
       Region 4xmn D 656-660 disorder
       Region 4xmn D 661-675 order
       Region 4xmn D 676-684 disorder
       Region 4xmn D 685-699 order
       Region 4xmn D 700-706 disorder
       Region 4xmn D 707-719 order
       Region 4xmn D 720-724 disorder
       Region 4xmn D 725-743 order
 
Prediction
NeProc
Disorder 1-59,445-451
Order 64-230,238-444,452-597,603-744
ProS 1-21,37-59
AlphaFold
Disorder 1-42,44-44,61-61,126-133,166-166,231-236,437-452,589-590,592-616,678-680,682-683,701-702,716-720,722-723,742-744
Order 43-43,45-60,62-125,134-165,167-230,237-436,453-588,591-591,617-677,681-681,684-700,703-715,721-721,724-741
SEG 646-652 ,727-739
Function
Function in SwissProt
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP85 is involved in nuclear poly(A)+ RNA and pre-ribosome export, in GSP1 nuclear import, in NPC assembly and distribution, as well as in nuclear envelope organization.