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IID50322
 UniprotP63170
ProteinDynein light chain 1, cytoplasmic
GeneDynll1
OrganismRattus norvegicus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
89
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-89 Homo dimer :
 Evidence NMR 1f3c A Reference
       Region 1f3c A 1-89 order
 Evidence NMR 1f3c B Reference
       Region 1f3c B 1-89 order
Seq 1-89 Hetero tetramer :
 Evidence NMR 1f96 A Reference
       Region 1f96 A 1-89 order
 Evidence NMR 1f96 B Reference
       Region 1f96 B 1-89 order
Seq 1-89 Hetero tetramer : IID00746Complex
 Evidence NMR 1f95 A Reference
       Region 1f95 A 1-89 order
 Evidence NMR 1f95 B Reference
       Region 1f95 B 1-89 order
Seqphosphorylation
    88-88 Phosphoserine
Seqacetylation
    36-36 N6-acetyllysine
 
Prediction
NeProc
Order 1-89
AlphaFold
Disorder 1-3
Order 4-89
Pfam Hmmer
PF01221 1-89 4.6e-64
Function
Function in SwissProt
Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.