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IID50328
UniprotQ1PS67
ProteinTelomerase reverse transcriptase
Genetert
OrganismOryzias latipes
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
1090
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 318-572 Monomer :
 Evidence X-RAY 4o26 B Reference
       Region 4o26 B 318-356 order
       Region 4o26 B 357-368 disorder
       Region 4o26 B 369-472 order
       Region 4o26 B 473-473 disorder
       Region 4o26 B 474-489 order
       Region 4o26 B 490-496 disorder
       Region 4o26 B 497-564 order
       Region 4o26 B 565-572 disorder
 Evidence X-RAY 4o26 A Reference
       Region 4o26 A 318-358 order
       Region 4o26 A 359-366 disorder
       Region 4o26 A 367-465 order
       Region 4o26 A 466-470 disorder
       Region 4o26 A 471-533 order
       Region 4o26 A 534-537 disorder
       Region 4o26 A 538-572 order
 
Prediction
NeProc
Disorder 1-3,176-308,361-375,1061-1071
Order 4-107,114-175,309-360,376-1060,1072-1090
ProS 1-3,197-202,222-303,361-375,1061-1071
AlphaFold
Disorder 1-4,104-112,177-311,323-324,407-412,491-494,708-708,723-728,756-756,816-816,868-875,919-921,1015-1021,1079-1079,1081-1084,1086-1086
Order 5-103,113-176,312-322,325-406,413-490,495-707,709-722,729-755,757-815,817-867,876-918,922-1014,1022-1078,1080-1080,1085-1085,1087-1090
SEG 217-257 ,282-292 ,1059-1072
Function
Function in SwissProt
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.