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IID00060
 UniprotP63098
ProteinCalcineurin subunit B type 1
GenePPP3R1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
170
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-170 Hetero trimer : IID00069Complex,P62937
 Evidence X-RAY 1mf8 B Reference
       Region 1mf8 B 1-5 disorder
       Region 1mf8 B 6-169 order
       Region 1mf8 B 170-170 disorder
Seq 1-170 Hetero dimer : P16298
 Evidence X-RAY 4orc B Reference
       Region 4orc B 1-4 disorder
       Region 4orc B 5-170 order
 Evidence X-RAY 4ora B Reference
       Region 4ora B 1-4 disorder
       Region 4ora B 5-170 order
 Evidence X-RAY 4or9 B Reference
       Region 4or9 B 1-4 disorder
       Region 4or9 B 5-170 order
Seq 1-170 Hetero trimer : IID00069Complex,IID90028Complex
 Evidence X-RAY 4f0z B Reference
       Region 4f0z B 1-6 disorder
       Region 4f0z B 7-161 order
       Region 4f0z B 162-170 disorder
Seq 1-170 Hetero trimer : IID00069Complex,IID00435Complex
 Evidence X-RAY 5sve B Reference
       Region 5sve B 1-5 disorder
       Region 5sve B 6-170 order
Seq 2-170 Hetero dimer : IID00069Complex
 Evidence X-RAY 3ll8 D Reference
       Region 3ll8 D 16-170 order
 Evidence X-RAY 1aui B Reference
       Region 1aui B 2-5 disorder
       Region 1aui B 6-170 order
Seq 2-170 Hetero hexamer : IID00069Complex,P62937
 Evidence X-RAY 1m63 F Reference
       Region 1m63 F 2-10 disorder
       Region 1m63 F 11-170 order
 Evidence X-RAY 1m63 B Reference
       Region 1m63 B 2-12 disorder
       Region 1m63 B 13-170 order
Seq 16-170 Hetero pentamer : IID00069Complex
 Evidence X-RAY 2p6b D Reference
       Region 2p6b D 16-168 order
       Region 2p6b D 169-170 disorder
 Evidence X-RAY 2p6b B Reference
       Region 2p6b B 16-161 order
       Region 2p6b B 162-170 disorder
Seq 16-170 Hetero trimer : IID00069Complex
 Evidence X-RAY 3ll8 B Reference
       Region 3ll8 B 16-170 order
Seqphosphorylation
    106-106 Phosphotyrosine
 
Prediction
NeProc
Disorder 1-10
Order 11-170
ProS 1-10
AlphaFold
Disorder 1-12
Order 13-170
Pfam Hmmer
PF00036 54-82 3e-06
PF00036 91-119 7.2e-06
PF00036 132-160 2.9e-06
Function
Function in SwissProt
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
Biological Process
See also
Diagram with PDB data
NFATC1/PPP3CA/PPP3R1Structure of Calcineurin in complex with NFATc1 LxVP peptide
PPP3CA/CALM1Structure of calmodulin bound to its recognition site from calcineurin
PPP3CA/RCAN1Structure of Calcineurin bound to RCAN1